Encoded Therapeutics is a clinical-stage genetic medicines company developing potentially disease-modifying therapies to improve the lives of people with severe CNS disorders. Our proprietary vector engineering approach combines novel regulatory elements and payloads with AAV vectors to unlock innovative solutions for debilitating, intractable CNS conditions. At the forefront is our flagship clinical program, ETX101 for Dravet syndrome, which targets the underlying cause of the disorder to enable highly selective upregulation of SCN1A for potentially long-lasting benefit. In parallel, we are advancing a pipeline of potentially best-in-class programs to address significant unmet needs across both monogenic and prevalent CNS conditions. For more information, please visit www.encoded.com .
We are recruiting an Engineer, Process Sciences to join our team. This is a unique opportunity to work at the intersection of genomics and therapeutics and participate in the development of a diverse therapeutic pipeline driven by a transformative core technology. The successful candidate will work well across multiple projects in a fast-paced and dynamic environment.
Responsibilities
Design, execute, and analyze small-scale studies supporting the development of two at-scale products and Encoded’s pipeline products
Serve as an engineer responsible for pre-clinical and clinical manufacturing for AAV projects and plasmid manufacturing; including upstream, downstream, fill finish, and drug device
Facilitate Encoded’s technology transfer of manufacturing processes to non-GMP/GMP internal and external sites of manufacturing
Provide person-in-plant support of GMP (clinical and commercial) manufacturing as required at internal and external sites of manufacturing
Work with cross-functional teams to develop tools/templates to support tech transfer business processes
Requirements
B.S or M.S. in a relevant area of specialization (biochemical engineering, chemical engineering, biological sciences, virology, molecular biology, or biochemistry)
At least 3 years of industry experience or equivalent educational experience
At least 1 year of industry experience in MSAT/PD/Process Sciences role preferred
Extensive working knowledge of modern laboratory procedures and knowledge of cGMP is a must
Ability to independently design, execute, and analyze small-scale purification studies (column chromatography, tangential flow filtration) is a must
Must be a team player and exhibit a willingness to meet project timelines
Strong verbal and written skills are required as well as effective interpersonal, technical, and troubleshooting skills
Outstanding planning, organization, and multitasking skills
Experience with fill-finish operations is strongly preferred
Benefits
Comprehensive benefits package, including competitive employer premium contributions
Meaningful stock option grants
PTO, sick time, and holiday pay
Generous Parental Leave program
Pre-tax medical and dependent care programs
STD, LTD, Life and AD&D
Professional development opportunities
Team-building events
Fully stocked kitchen
Employees (and their families) may obtain medical, dental, vision and basic life insurance benefits through the company and enroll in our company's 401k plan. Employees will also accrue vacation time off and paid sick time off and may become eligible for paid parental leave. Employees will also enjoy designated paid holidays throughout the calendar year.
Encoded is an Equal Opportunity Employer and prohibits discrimination and harassment of any kind. Encoded is committed to the principle of equal employment opportunity for all employees and to providing employees with a work environment free of discrimination and harassment. All employment decisions at Encoded are based on business needs, job requirements and individual qualifications, without regard to race, religion or belief, color, national origin, gender, status as a protected veteran, status as an individual with a disability, or any other status protected by the laws or regulations in the location in which we operate. Encoded will not tolerate discrimination or harassment based on any of these characteristics. Encoded encourages applicants of all ages.
If you need assistance or an accommodation due to a disability, you may call us at +1 650-491-0272.
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